Cellular Response to Stress
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Field of study
- Barrier properties of cell membranes and molecular bioenergetics. This direction is relevant to biomedicine as research aims to increase the effectiveness of treatment for infectious diseases. The interaction of bacteria, yeast, and microscopic fungi with biocidal compounds and viruses, seeking ways to increase the effectiveness of well-known antimicrobial compounds by enhancing their interaction with microorganisms are being sought. Newly synthesized compounds causing stress to microorganisms are being studied. New ways of (1) increasing the permeability of microbial envelopes and (2) inhibiting the activity of efflux pumps are being sought. New methods for rapid determination of the viability of microorganisms are also being developed, the response of biofilm-forming microorganisms to antibiotics and fungicides is studied by the laser point contrast method, the causes and mechanisms of the barrier of the plasma membrane of metabolically active cells to lipophilic anions are analyzed.
- Plant biochemistry focused on the applied potential of plant stress response. This direction is related to the development of innovative advanced and sustainable agricultural methods, based on the knowledge of molecular mechanisms of plant plasticity, adaptation, and stress response. In collaboration with members of the international plasma agriculture network https://plagri.eu/, the research will investigate molecular mechanisms of plant responses to seed treatment with physical stressors such as low-temperature plasma (cold plasma, CP), vacuum, or electromagnetic field (EMF). The obtained knowledge is expected to be used in the development of methods for promoting plant productivity, stress resistance and secondary metabolic activity, with special attention paid to the bioproduction of pharmacologically important medicinal substances. Experiments in the laboratory, greenhouse, and field will be conducted on different combinations of seed treatment with plasma-activated water (PAW), testing the application of physical seed stressors and PAW for aeroponic and vertical plant cultivation. In collaboration with industrial partners, the goal is to develop treatment systems that can be adapted for household and greenhouse use, preparing protocols, prototypes, and guidelines on how to use these systems in farms and industry.
People
Principal Scientists
Senior Scientists
Researchers
Junior Scientists
Doctoral Students
Defended dissertations (over the last 5 years)
2023
Sandra Sakalauskaitė. “Characteristics of multidrug efflux pump inhibitors: the interaction with bacteria and the role in reducing antibiotic resistance”. Natural sciences, Biochemistry – N 004. Scientific supervisor Prof. dr. R. Daugelavičius.
Anatolii Ivankov. “Impact of seed treatment with cold plasma and electromagnetic field on plant growth, content of secondary metabolites, and microbiota”. Natural sciences, Biochemistry – N 004. Scientific supervisor Prof. habil. dr. V. Mildažienė.
2020
Projects
2025-2027. Lithuanian-Latvian-Taiwanese Cooperation Project “Exploring the Organellar Homeostasis in Senescent Yeast Model: Mechanisms and Implications for Geriatric Health”. Lithuanian part led by R. Daugelavicius.
2024-2026. Project S-LJB-24-1 „Molecular mechanisms underlying effects of seed treatment with cold plasma and plasma activated water“, the Bilateral (Lithuania-Japan) cooperation program, Lithuanian Research Council. Position – project investigator.
2024-2025. Lithuanian-Ukrainian program project “Genetic control of transmembrane transport and metabolism of pentose sugars in Ogataea polymorpha yeast during alcoholic fermentation”. Lithuanian part led by R. Daugelavicius.
2023-2025. Lithuanian Research Council Researchers group project P-MIP-23-160 „Application of plasma and aeroponic technologies for increasing plant biomass gain and yield of biologically active compounds“. Position: principal investigator.
2021-2023. Project of targeted research in the field of smart specialization. “Modulation of industrial hemp target metabolites to develop products to alleviate symptoms of COVID-19” (13.1.1-LMT-K-718-05-0039). Partner coordinator.
2020-2024. COST project CA19110 – Plasma applications for smart and sustainable agriculture. National coordinator.
2020-2022. “Development of innovative magnesium and calcium citrate prototypes” under the 2014-2020 European Union Funds Investment Action Program Priority 1 “Promotion of research, experimental development and innovation” implementation measure No. 01.2.1-LVPA-K-856 “EXPERIMENT”. VMU section led by R. Daugelavicius.
2020. Baltic-Deutshes Hochschulkontor Project “Plasma application in agriculture: seed treatment with plasma as an alternative method for increasing plant productivity” Project leader.
2020. Inter-institutional Santaka Valley project P20-BS1-128 “Innovative technologies for increasing production of biologically active plant metabolites” Leader of VMU part
2019-2021. Project P-LJB-19-6 „Early development of seedling stress response to seed treatment with component-controlled cold plasma“, the Bilateral (Lithuania-Japan) cooperation program, Lithuanian Research Council. Position – project leader.
2019-2021. Project P-LB-19-13 “Development of Methods for Control of Quantity and Composition of Pharmacologically Valuable Compounds (Secondary Metabolites) in Plant Tissue by Plasma and Radio Frequency Seed Treatment” supported by the Bilateral (Lithuania-Belarus) Cooperation Program Lithuanian Research Council. Position – project leader.
2019. „Cotton waste recycling through microbiological hydrolysis and ethanol fermentation (CotEtha)“ VMU-KTU joint activity project PP-88D/19. VMU group leader R. Daugelavicius.
2018-2019. Vytautas Magnus university research cluster project „Changes in red clover root nodulation and composition of root exudates caused by seed treatments by stressors“. P-FB-18-04. Position – project leader.
2018-2019. Lithuanian-Ukrainian program project “Design of xylose transport in thermotolerant yeast Ogataea polymorpha for improving alcoholic fermentation”. Lithuanian part led by R. Daugelavicius.
2017-2019. Lithuanian Research Council Researchers group project „Involvement of oxidative stress in molecular mechanism of seed response to cold plasma treatment“ (S-MIP-17-53). Position: principal investigator, VMU coordinator.
2017-2019. Project “Search for ways to overcome the resistance of yeast of the genus Candida to antifungal compounds” of the activity “Promotion of post-doctoral internships”. Leader R. Daugelavicius, executor Dr. Simona Vaitkienė.
2016-2018. Lithuanian-Latvian-Taiwanese cooperation project “Studies of intracellular changes in yeast during anhydrobiosis applicable to biomedicine and biotechnology”. Lithuanian part led by R. Daugelavicius.
2016-2017. Vytautas Magnus university research cluster project „Estimation of changes in dynamics of plant hormones induced by seed treatment with physical stressors“. Position – project leader.
2015-2017. Project “Increasing the efficiency of antibacterial and cytostatic drugs by enhancing their interaction with cells” implemented at the initiative of the Lithuanian Science Council Scientists. Led by R. Daugelavicius.
2015-2016. EEE and Norvegian Environment Agency, grant priority sector Environmental protection and management programme LT03 Biodiversity and ecosystem services “Estimation of an impact of climate change on biological diversity in The Southwest Lithuania and development of measures for adjustment (Botanica sudavica)”. Position – project leader.
Lithuanian Research Council.
Patents
Patent Nr. 6922
“The method for the increase of steviol glycosides amount in stevia plants by seed treatment with cold plasma before sowing” (03/12/2020) at The State Patent Bureau of the Republic of Lithuania. Iinventors: Rasa Žūkienė, Vida Mildažienė.
Patent Nr. 6924
“The method for the increase of non-psychotropic cannabinoids amount in industrial hemp (Cannabis sativa) in leaves and inflorescences by seed treatment with vacuum before sowing” (04/12/2020) at The State Patent Bureau of the Republic of Lithuania. Inventors: Rasa Žūkienė, Vida Mildažienė, Zita Naučienė.
Publications
2024
Bilea, F.; Garcia-Vaquero, M.; Magureanu, M.; Mihaila, I.; Mildažienė, V.; Mozetič, M.; Pawlat, J.; Primc, G.; Puač, N.; Robert, E.; Stancampiano, A.; Topala, I; Žūkienė, R. Non-Thermal Plasma as Environmentally-Friendly Technology for Agriculture: A Review and Roadmap. Critical Reviews in Plant Sciences 2024, 1–59. https://doi.org/10.1080/07352689.2024.2410145
Mildažienė, V.; Žukienė, R.; ˙ Degutytė-Fomins, L.; Naučiene, Z.; Minkutė,˙ R.; Jarukas, L.; Drapak, I.; Georgiyants, V.; Novickij, V.; Koga, K. Effects of Corm Treatment with Cold Plasma and Electromagnetic Field on Growth and Production of Saffron Metabolites in Crocus sativus. Int. J. Mol. Sci. 2024, 25, 10412. https://doi.org/10.3390/ijms251910412
Čėsnienė, I.; ˙Čėsna, V.; ˙ Miškelytė, D.; Novickij, V.; ˙ Mildažienė, V.; Sirgedaitė-Šežienė, V. Seed Treatment with Cold Plasma and Electromagnetic Field: Changes in Antioxidant Capacity of Seedlings in Different Picea abies (L.) H. Karst Half-Sib Families. Plants 2024, 13, 2021. https://doi.org/10.3390/plants13152021
Okumura, T., Anan, T., Shi, H., Attri, P., Kamataki, K., Yamashita, N., Itagaki, N., Shiratani, M., Ishibashi, Y., Koga, K., Mildaziene, V. Response of lettuce seeds undergoing dormancy break and early senescence to plasma irradiation. Appl. Phys. Express 2024, 17, 057001. https://doi.org/10.35848/1882-0786/ad3798
Žaltauskaitė, J., Meištininkas, R., Dikšaitytė, A., Degutyte-Fomins, L., Mildaziene, V., Nauciene, Z., Zukiene, R., Koga, K. Heavy fuel oil-contaminated soil remediation by individual and bioaugmentation-assisted phytoremediation with Medicago sativa and with cold plasma-treated M. sativa. Environ Sci Pollut Res 31, 30026–30038, 2024. https://doi.org/10.1007/s11356-024-33182-4
Sakalauskaitė, S., Mikalayeva, V., Sutkuvienė, S., Daugelavičius, R. Mode of the Interaction of Efflux Inhibitor Phenylalanyl-arginyl-β-naphtylamide with Bacterial Cells. Biomedicines 2024, 12, 1324. https://doi.org/10.3390/biomedicines12061324
Daugelavičius, R.; Daujotaitė, G.; Bamford, D.H. Lysis Physiology of Pseudomonas aeruginosa Infected with ssRNA Phage PRR1. Viruses 2024, 16, 645. https://doi.org/10.3390/v16040645
2023
Lelis M.; Tuckute S.; Urbonavicius M.; Varnagiris S.; Sakalauskaite S.; Daugelavicius, R. C-TiO2+Ni and ZnO+Ni magnetic photocatalyst powder synthesis by reactive magnetron sputtering technique and their application for bacteria inactivation. Inorganics 2023, 11(2), 59. https://doi.org/10.3390/inorganics11020059
Gudynienė, V.; Juzėnas, S.; Stukonis, V.; Mildažienė, V.; Ivankov, A.; Norkevičienė, E. Comparing Non-Thermal Plasma and Cold Stratification: Which Pre-Sowing Treatment Benefits Wild Plant Emergence? Plants 2023, 12, 3220. https://doi.org/10.3390/plants12183220
Čėsniene I, Miškelytė D, ˙ Novickij V, Mildažienė V, ˙ Sirgedaite-Šežienė V. Seed Treatment ˙ with Electromagnetic Field Induces Different Effects on Emergence, Growth and Profiles of Biochemical Compounds in Seven Half-Sib Families of Silver Birch. Plants 2023, 12, 3048. https://doi.org/10.3390/plants12173048
Judickaitė A, Venckus J, Koga K, Shiratani M, Mildažienė V, Žūkienė R. Cold Plasma-Induced Changes in Stevia rebaudiana Morphometric and Biochemical Parameter Correlations. Plants 2023, 12, 1585. https://doi.org/10.3390/plants12081585
2022
Sirgedaitė-Šėžienė V, Lučinskaitė I, Mildažienė V, Ivankov A, Koga K, Shiratani M, Laužikė K, Baliuckas V. Changes in Content of Bioactive Compounds and Antioxidant Activity Induced in Needles of Different Half-Sib Families of Norway Spruce (Picea abies (L.) H. Karst) by Seed Treatment with Cold Plasma. Antioxidants. 2022; 11(8):1558. https://doi.org/10.3390/antiox11081558
Mildaziene V, Sera B. Effects of Non-Thermal Plasma Treatment on Plant Physiological and Biochemical Processes. Plants (Basel). 2022 Apr 8;11(8):1018. https://doi.org/10.3390/plants11081018
Mildaziene V, Ivankov A, Sera B, Baniulis D. Biochemical and Physiological Plant Processes Affected by Seed Treatment with Non-Thermal Plasma. Plants. 2022; 11(7):856. https://doi.org/10.3390/plants11070856
Judickaitė A, Lyushkevich V, Filatova I, Mildažienė V, Žūkienė R. The Potential of Cold Plasma and Electromagnetic Field as Stimulators of Natural Sweeteners Biosynthesis in Stevia rebaudiana Bertoni. Plants (Basel). 2022 Feb 24;11(5):611. https://doi.org/10.3390/plants11050611
2021
Vasiliauske D, Sakalauskaite S, Kuliesiene N, Tuckute S, Urbonavicius M, Varnagiris S, Daugelavicius R and Lelis M. Synergistic Generation of Reactive Oxygen Species by Visible Light Activated TiO2 and S. Enterica Interaction. Environmental and Climate Technologies, 2021, vol.25, no.1, pp.978-989. https://doi.org/10.2478/rtuect-2021-0074
Demikyte E., Sakalauskaite S., Kuliesiene N., Tuckute S., Urbonavicius M., Varnagiris S., Daugelavicius R., Lelis M. Ni underlayer effect for the structure development and visible light photocatalytic efficiency of carbon-doped TiO2 film. Environmental and Climate Technologies 2021, vol. 25, no. 1, pp. 1032–1042. http://doi.org/10.2478/rtuect-2021-0078
Sakalauskaite, S.; Vasiliauske, D.; Demikyte, E.; Daugelavicius, R.; Lelis, M. Influence of the Metabolic Activity of Microorganisms on Disinfection Efficiency of the Visible Light and P25 TiO2 Photocatalyst. Catalysts 2021, 11, 1432. https://doi.org/10.3390/catal11121432
Anes J, Dever K, Eshwar A, Nguyen S, Cao Y, Sivasankaran SK, Sakalauskaitė S, Lehner A, Devineau S, Daugelavičius R, Stephan R, Fanning S, Srikumar S. Analysis of the oxidative stress regulon identifies soxS as a genetic target for resistance reversal in multidrug-resistant Klebsiella pneumoniae. mBio 2021, 12:e00867-21. https://doi.org/10.1128/mBio.00867-21
Sakalauskaitė, S., Mikalayeva, V., Daugelavičius, R. Ethidium Binding to Salmonella enterica ser. Typhimurium Cells and Salmon Sperm DNA. Molecules 2021, 26, 3386. https://doi.org/10.3390/molecules26113386
Chen, C-L., Huang, W.-L., Chen, Y.-Ch., Lin, S., Daugelavičius, R., Rapoport, A., Chang, Ch-R. Mitochondria Dynamics Machinery is Required for Resistant to Dehydration in Saccharomyces cerevisiae. International Journal of Molecular Sciences 2021, 22, 4607. https://doi.org/10.3390/ijms22094607
Kubiliute R., I. Januskeviciene, R. Urbanaviciute, K. Daniunaite, M.Drobniene, V. Ostapenko, R. Daugelavicius, S. Jarmalaite. Nongenotoxic ABCB1 activator tetraphenylphosphonium can contribute to doxorubicin resistance in MX-1 breast cancer cell line. Scientific Reports, 2021, 11:6556. https://doi.org/10.1038/s41598-021-86120-6
Vaitkienė S., Kuliešienė N., Sakalauskaitė S., Bekere L., Krasnova L., Vigante B., Duburs G., and Daugelavičius R. Antifungal activity of styrylpyridinium compounds against Candida albicans. Chem Biol Drug Design 2021, 97 (2):1-13. https://onlinelibrary.wiley.com/doi/10.1111/cbdd.13777
Yousef S., Kuliešienė N., Sakalauskaitė S., Nenartavičius T., Daugelavičius R. Sustainable green strategy for recovery of glucose from end-of-life euro banknotes. Waste Management 2021, 123(2) :23-32. https://doi.org/10.1016/j.wasman.2021.01.007
Kuliešienė, N., Žūkienė, R., Khroustalyova, G., Chang, C.-R., Rapoport, A., Daugelavičius, R. Changes in Energy Status of Saccharomyces cerevisiae Cells during Dehydration and Rehydration. Microorganisms 2021, 9, 444. https://doi.org/10.3390/microorganisms9020444
Vaitkienė, S., Bekere, L., Duburs, G., Daugelavičius, R. Interaction of Styrylpyridinium .Compound with Pathogenic Candida albicans Yeasts and Human Embryonic Kidney HEK-293 Cells. Microorganisms 2021, 9, 48. https://dx.doi.org/10.3390/microorganisms9010048
Ivankov, A.; Naučiene, Z.; ˙ Degutyte-Fomins, L.; Žūkienė, R.; ˙ Januškaitiene, I.; Malakauskienė, A.; ˙ Jakštas, V.; Ivanauskas, L.; Romanovskaja, D.; Šlepetiene, A.; Filatova, I.; Lyushkevich, V.; Mildažienė V. Changes in Agricultural Performance of Common Buckwheat Induced by Seed Treatment with Cold Plasma and Electromagnetic Field. Appl. Sci. 2021, 11, 4391.
Kuliešienė N., Žūkienė R., Khroustalyova G., Chang Ch.-R., Rapoport A., Daugelavičius R. Changes in energy status of Saccharomyces cerevisiae cells during dehydration and rehydration. Microorganisms. 2021, 9(2), 1-13. https://doi.org/10.3390/microorganisms9020444
Ivankov, A.; Zukiene, R.; Nauciene, Z.; Degutyte-Fomins, L.; Filatova, I.; Lyushkevich, V.; Mildaziene, V. The Effects of Red Clover Seed Treatment with Cold Plasma and Electromagnetic Field on Germination and Seedling Growth Are Dependent on Seed Color. Appl. Sci. 2021, 11, 4676. https://doi.org/10.3390/app11104676
Attri, P., Ishikawa K.; Okumura, T.; Koga, K.; Shiratani M.; Mildaziene, M. Impact of seed color and storage time on the radish seed germination and sprout growth in plasma agriculture. Sci. Rep. 2021, 11, 2539. https://doi.org/10.1038/s41598-021-81175-x
2020
Ivankov, A., Nauciene, Z., Zukiene, R., Degutyte-Fomins, L., Malakauskiene, A., Kraujalis, P., Venskutonis, P.R., Filatova, I., Lyushkevich, V., Mildaziene V. Changes in growth and production of non-psychotropic cannabinoids induced by pre-sowing treatment of hemp seeds with cold plasma, vacuum and electromagnetic field, Applied Sciences, 2020, 10(23), 8519. https://doi.org/10.3390/app10238519
Blinstrubienė A., Burbulis N., Juškevičiūtė N., Vaitkevičienė N., Žūkienė R. Effect of growth regulators on Stevia rebaudiana Bertoni callus genesis and influence of auxin and proline to steviol glycosides, phenols, flavonoids accumulation, and antioxidant activity in vitro. Molecules. 2020, 25 (12), 1-15. https://doi.org/10.3390/molecules25122759
Sirgedaitė‐Šėžienė, V., Mildažienė, V., Žemaitis, P., Ivankov, A., Koga, K., Shiratani, M., & Baliuckas. Long‐term response of Norway spruce to seed treatment with cold plasma: Dependence of the effects on the genotype. Plasma Proc. Polym. 2020. https://doi.org/10.1002/ppap.202000159
Tamošiūnė, I., Gelvonauskienė, D., Haimi, P., Mildažienė, V., Koga, K., Shiratani, M., & Baniulis, D. Cold Plasma Treatment of Sunflower Seeds Modulates Plant-Associated Microbiome and Stimulates Root and Lateral Organ Growth. Frontiers in Plant Science, 2020, 11. https://doi.org/10.3389/fpls.2020.568924
Mildažienė V., Ivankov, A., Paužaitė G., Naučienė Z., Žūkienė R., Degutytė-Fomins, Pukalskas A., Venskutonis P.R., Filatova I., Lyuskevich V. Seed treatment with cold plasma and electromagnetic field induces changes in red clover root growth dynamics, flavonoid exudation, and activates nodulation. Plasma Proc. Polym. 2020, 18(2), 2000160. https://doi.org/10.1002/ppap.202000160
Mildažienė V., Paužaitė G., Naučienė Z., Žūkienė R., Malakauskienė A., Norkevičienė E., Šlepetienė A., Stukonis V., Olšauskaitė V., Padarauskas A., Filatova I., Lyuskevich V. Effect of seed treatment with cold plasma and electromagnetic field on red clover germination, growth and content of major isoflavones. J. Phys. D: Appl. Phys. 2020, 53, 264001. https://doi.org/10.1088/1361-6463/ab8140
Koga K., P. Attri, K. Kamataki, N. Itakagi, Shiratani M. , Mildažienė V. Impact of radish sprouts seeds coat color on the electron paramagnetic resonance signals after plasma treatment. Jpn. J. Appl. Phys., 59, SHHF01, 2020. https://doi.org/10.35848/1347-4065/ab7698
Degutytė-Fomins L., Paužaitė G., Žukienė R., Mildažienė V., Koga K., Shiratani M. Relationship between cold plasma treatment-induced changes in radish seed germination and phytohormone balance Jpn. J. Appl. Phys., 59, SH1001, 2020. https://iopscience.iop.org/article/10.7567/1347-4065/ab656c
Kuliesiene N., Sakalauskaite S., Tuckute S., Urbonavicius M., Varnagiris S., Daugelavicius R., Lelis M. TiO2 Application for the Photocatalytical Inactivation of S. enterica, E. coli and M. luteus Bacteria Mixtures. Environmental and Climate Technologies 2020, vol. 24, no. 3, pp. 418–429. https://doi.org/10.2478/rtuect-2020-0113
Sakalauskaite S., Kuliesiene N, Galalyte N., Tuckute S., Urbonavicius M., Varnagiris S., Daugelavicius R., Lelis M. Potential and Risk of the Visible Light Assisted Photocatalytical Treatment of PRD1 and T4 Bacteriophage Mixtures. Environmental and Climate Technologies 2020, vol. 24, no. 3, pp. 215–224. https://doi.org/10.2478/rtuect-2020-0098
Tamošiūnas M. Vaitkienė S., Mikštaitė N., Galalytė D., Kuliešienė N., Cugmas B., Lihachev A., Daugelavičius R. Assessment of Candida albicans biofilm growth by laser speckle contrast imaging. Proc. SPIE 11585, Biophotonics—Riga 2020, 1158509. https://doi.org/10.1117/12.2582216
Ragelienė L., Paulauskaitė R., Trečiokaitė L.,Žūkienė R., Daugelavičius R., Tučkutė S., and Bendoraitienė J. 2020. Impact of BaSO4 particles on the viability of eukaryotic and prokaryotic cells. J Pharmacy Pharmacol, 8:361-373.
Vaitkienė S, Daugelavičius R, Sychrová H and Kodedová M. Styrylpyridinium derivatives as new potent antifungal drugs and fluorescence probes. Front. Microbiol. 2020, 11:2077. https://doi.org/10.3389/fmicb.2020.02077
Vasylyshyn R., Kurylenko O., Ruchala, J., Shevchuk, N., Kuliesiene N., Khroustalyova, G., Rapoport A., Daugelavicius R., Dmytruk K., and Sibirny A. Engineering of sugar transporters for improvement of xylose utilization during high‑temperature alcoholic fermentation in Ogataea polymorpha yeast. Microb. Cell Fact. 2020, 19:96. https://doi.org/10.1186/s12934-020-01354-9
Sutkuvienė S, Sakalauskaitė S, Kuliešienė N, Ragelienė L, Daugelavičius R. Evaluation of antimicrobial activity of synthesized 9H-alkylcarbazole and 10H-alkylphenothiazine derivatives on the cells of Salmonella enterica ser. Typhimurium, Saccharomyces cerevisiae, and Candida albicans. Biologija 2020, 66 (2):80–93. https://doi.org/10.6001/biologija.v66i2.4255
Varnagiris S., Urbonavicius M., Sakalauskaite S., Daugelavicius R., Pranevicius L., Lelis M., Milcius D. Floating TiO2 photocatalyst for efficient inactivation of E. coli and decomposition of methylene blue solution. Sci. Total Environ. 2020, 720:137600. https://doi.org/10.1016/j.scitotenv.2020.137600
2019
Kurylenko, O., Rozenfelde, L., Khroustalyova, G., Vasylyshyn, R., Ruchala, J., Chang, C-R., Daugelavicius, R., Sibirny, A., Rapoport A. Anhydrobiosis in yeasts: Glutathione synthesis by yeast Ogataea (Hansenula) polymorpha cells after their dehydration-rehydration. J. Biotechnol. 2019, 304:28–30. https://doi.org/ 10.1016/j.jbiotec.2019.08.005
Vaičiukynė M., Žiauka J., Žūkienė R., Vertelkaitė L., Kuusienė, S. Abscisic acid promotes root system development in birch tissue culture: a comparison to aspen culture and conventional rooting‐related growth regulators. Physiologia Plantarum. 2019, 165(1), 114-122. (IF 3.00). https://doi.org/10.1111/ppl.12860
2018
Šilkūnienė G., Žūkienė R., Naučienė Z., Degutytė-Fomins L., Mildažienė V. Impact of Gender and Age on Hyperthermia-Induced Changes in Respiration of Liver Mitochondria. Medicina. 2018, 54(4), 1-14. (IF 1,467). https://doi.org/10.3390/medicina54040062
Satkauskiene I., Wood T., Rutkauskaite-Suciliene J., Mildaziene V., Tuckute S. Freshwater bryozoans of Lithuania (Bryozoa). ZooKeys 2018, 774(3):53-75. https://doi.org/10.3897/zookeys.774.21769
Bondarenko OM, Sihtmäe M, Kuzmičiova J, Ragelienė L, Kahru A, Daugelavičius R. Plasma membrane is the target of rapid antibacterial action of silver nanoparticles in Escherichia coli and Pseudomonas aeruginosa. Int J Nanomedicine. 2018; 13:6779-6790. https://doi.org/10.2147/IJN.S177163
Tatariants, M., Yousef, S., Sakalauskaitė, S., Daugelavičius, R., Denafas, G., Bendikiene, R. Antimicrobial copper nanoparticles synthesized from waste printed circuit boards using advanced chemical technology. Waste Management 2018; 78(8):521-531. https://doi.org/10.1016/j.wasman.2018.06.016
Kulikova-Borovikova, D., Khroustalyova, G., Chang, C.-R., Daugelavicius, R., Yurkiv, M., Ruchala, J., Sibirny, A., Rapoport, A. Anhydrobiosis in yeast: Glutathione overproduction improves resistance to dehydration of a recombinant Ogataea (Hansenula) polymorpha strain. Proc Biochem. 2018; 71 (8): 41-44. https://doi.org/10.1016/j.procbio.2018.05.016
2017
Tamosiunas M, Kuliešienė N, Daugelavicius R. Implicit dosimetry of microorganism photodynamic inactivation. Proc. SPIE 10592, Biophotonics—Riga 2017, 105920K. https://doi.org/10.1117/12.2297221
Varnagiris, S, S. Sakalauskaite, S. Tuckute, M. Lelis, R. Daugelavicius and D. Milcius. Investigation of E. coli bacteria inactivation by photocatalytic activity of TiO2 coated expanded polystyrene foam. Materials Research Express. 2017; 4(3). https://doi.org/10.1088/2053-1591/aa6604
Mikalayeva V, Sakalauskaitė S, Daugelavičius R. Interaction of ethidium and tetraphenylphosphonium cations with Salmonella enterica cells. Medicina (Kaunas). 2017; 53(2):122-130. https://doi.org/10.1016/j.medici.2017.04.001
Žūkienė R., Naučienė Z., Šilkūnienė G., Vanagas T., Gulbinas A., Zimkus A. , Mildažienė. Contribution of mitochondria to injury of hepatocytes and liver tissue by hyperthermia. Medicina, 2017, 53(1), 40-49. (IF 1,429). https://doi.org/10.1016/j.medici.2017.01.001
2016
Mildaziene V., Pauzaite G., Malakauskiene A., Zukiene R., Nauciene Z., Filatova I., Azharonok I., Lyushkevich V. Response of Perennial Woody Plants to Seed Treatment by Electromagnetic Field and Low-Temperature Plasma. Bioelectromagnetics. 2016, 37, 536-548. (IF 1,933). https://doi.org/10.1002/bem.22003
Mikučionienė, D., R. Milašius, R. Daugelavičius, L. Ragelienė, N. Venslauskaitė, A. Ragaišienė, Ž. Rukuižienė. Preliminary investigation into the antimicrobial activity of an electrospun polyamide nanofibrous web with micro particles of Baltic amber. FIBRES & TEXTILES in Eastern Europe 2016. 24, 5(119): 34-37. doi:10.5604/12303666.1215524
Orentaite I, Poranen MM, Oksanen HM, Daugelavicius R, Bamford DH. K2 killer toxin-induced physiological changes in the yeast Saccharomyces cerevisiae. FEMS Yeast Research. 2016; 16(2). https://doi.org/10.1093/femsyr/fow003
Svirskaitė J, Oksanen HM, Daugelavičius R, Bamford DH. 2016. Monitoring Physiological Changes in Haloarchaeal Cell during Virus Release. Viruses. 2016; 8(3): E59. https://doi.org/10.3390/v8030059
Kubiliūtė R, Šulskytė I, Daniūnaitė K, Daugelavičius R, Jarmalaitė S. Molecular features of doxorubicin-resistance development in colorectal cancer CX-1 cell line. Medicina (Kaunas). 2016; 52(5):298-306. https://doi.org/10.1016/j.medici.2016.09.003
2015
Žūkienė R., Snitka V. Zinc oxide nanoparticle and bovine serum albumin interaction and nanoparticles influence on cytotoxicity in vitro. Colloids and surfaces B: Biointerfaces, 2015. 135, 316-323. https://doi.org/10.1016/j.colsurfb.2015.07.054
2014
Antanavičiūtė I., Mildazienė V., Stankevičius E, Herdegen T., Skeberdis V. A. 2014. Hyperthermia differently affects connexin43 expression and gap junction permeability in skeletal myoblasts and HeLa cells. Mediators of Inflammation. Article ID 748290. http://dx.doi.org/10.1155/2014/748290